S-Acetyl Glutathione Synergy is a unique detox and antioxidant support supplement by Designs for Health that provides 200 mg of S-acetyl glutathione a highly absorbable form of the body's "master antioxidant" plus 1 g of NAC and 10 mg of vitamin B6 (as P5P) per serving.* Together, these ingredients help support healthy antioxidant status, normal detoxification, cellular health, immune function, a healthy inflammatory response, and healthy aging.* S-Acetyl Glutathione Synergy is formulated to support antioxidant status and normal detoxification pathways.* It directly delivers S-acetyl glutathione a stable, bioavailable form of the body's "master" antioxidant while also providing NAC, a key building block your body uses to naturally make more glutathione, for comprehensive antioxidative support.* Individual results may vary based on oxidative stress levels, diet, and overall health status.* Key benefits include support for antioxidant status, cellular repair, immune health, normal detoxification, and healthy aging supported by a powerful blend of S-acetyl glutathione, NAC (a building block for glutathione), and vitamin B6 (as P5P).* Take two capsules per day, or as directed by your healthcare practitioner

Glutathione acts like a cleanup crew for your skin, neutralizing the free radicals that cause these dark spots and other signs of aging
Free Radic Biol Med 175:236248 He Z, Shen P, Feng L, Hao H, He Y, Fan G et al (2022) Cadmium induces liver dysfunction and ferroptosis through the endoplasmic stress-ferritinophagy axis
In fact, it requires a large contribution of methyl groups