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in addition, no significant differences were observed between Lgr6 and Sox2 (Figure 5A)
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A triple combination targeting epigenetic dysregulation and apoptotic resistance, comprising iadademstat (LSD1 inhibitor), azacitidine (a hypomethylating agent), and venetoclax (a BCL-2 inhibitor), is under investigation in a phase I trial for acute myeloid leukemia (NCT06357182)
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