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In particular, it acts as a cofactor of antioxidant enzymes and also promotes the activity of other natural antioxidants such as vitamins C and E
The underlying mechanism is unclear, and hypotheses include changes in retinal blood flow and hemodynamics and upregulation of vascular endothelial growth factor, leading to retinal neovascularisation
We reviewed relevant peer-reviewed articles, preclinical and clinical studies, and systematic reviews published between 2012 and 2024, using databases such as Scopus, Web of Science, and PubMed
Virchows Arch B Cell Pathol 20: 217-228, 1976
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