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( i-j ) FT282-CCNE1 cells ( i ) and Ovcar8-CCNE1 cells ( j ) were treated with olaparib alone or in combination with the IDH1i or mildronate
The K1 cell line is a BRAF V600E -PI3KCA mutant, MDA-T32 is a BRAF V600E -TERT promoter mutant, and MDA-T68 is a NRAS and TERT promoter mutant, whereas TPC1 does not possess RAS or BRAF mutations
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