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Clinical translation would require trials in cardiac patient populations with appropriate safety monitoring given theoretical concerns about blood pressure effects and vascular remodeling
But, the process works even better when paired with a healthy lifestyle
After intravenous administration, MSCs initially localize to the lungs and liver before homing to target organs such as the kidneys, where they exert antidiabetic effects by mitigating inflammation and fibrosis, partly via the autophagy-mediated Sirtuin 1 (SIRT1)/Forkhead Box O1 pathway
No, not automatically
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