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Oxidative stress has been identified as having an important role in cerebrovascular disease and given increasing recognition of the overlap between vascular dementia and AD (mixed dementia) and the contribution of vascular changes to AD [93] investigating potential effects of cerebrovascular disease as a covariate would be an important direction for future studies

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doi: 10.3389/fonc.2021.702287 Received 29 April 2021 Accepted 02 July 2021 Published 19 July 2021 Volume 11 - 2021 Edited by Vladimir Spiegelman, Penn State Milton S

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