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432 A 2021 systematic review and meta-analysis that included 22 observational studies with a total of 440,281 elderly participants with atrial fibrillation taking rivaroxaban, dabigatran, apixaban, or edoxaban found these medications were associated with similar reductions in risks of stroke and other embolic events, but rivaroxaban was associated with more bleeding events than apixaban or edoxaban

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It is essential to follow the healthcare providers instructions and complete the entire course of treatment for the best results

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