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Monitoring Response Patients or research participants typically notice: Appetite suppression within the first 12 weeks Early satiety and slower gastric emptying by weeks 34 Weight loss trends becoming evident by week 8 Continued improvements in glucose metabolism when paired with semaglutide or tirzepatide Side Effects and Considerations Common side effects include: Nausea Mild gastrointestinal discomfort Constipation Injection site reactions These effects are generally transient and dose-dependent, which is why titration is important
It is recommended to use an ice compress on the affected area for intervals of 10 to 15 minutes
Diabetes (2012) 61(11):296779
It should not be used in people with a personal or family history of medullary thyroid carcinoma or in those with multiple endocrine neoplasia syndrome type 2, unless a doctor decides otherwise based on local guidance
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