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[51] Diagnosis [edit] According to one review: "At present, no 'gold standard' test exists for the diagnosis of vitamin B 12 deficiency and as a consequence the diagnosis requires consideration of both the clinical state of the patient and the results of investigations." [52] The vitamin deficiency is typically suspected when a routine complete blood count shows anemia with an elevated mean corpuscular volume (MCV)
-LA, a naturally occurring dithiol with antioxidant and anti-inflammatory function, can decrease the interaction between Nrf2 and Keap1, inhibit the pro-inflammatory cytokine IL-8 production and minimize the infection via the Nrf2/HO-1 pathway in the AGS cells (161)
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Further, the amino acid asparagine (Asn) at position eight is replaced with a modified amino acid called Lysine (Lys)
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