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In studies, some patients lost over 5-15% of their body weight with long-term use of GLP-1s like semaglutide and tirzepatide
This combination minimizes tissue trauma and injection pain while ensuring reliable subcutaneous delivery
2 STEP UP, 72-week study of adults with obesity using Wegovy (semaglutide 7.2mg)
Such studies are inherently susceptible to confounding by socioeconomic status, access to healthcare, reimbursement policies, and patient adherence, all of which may significantly impact treatment continuation and metabolic outcomes
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