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Una vez reconstituida, la solucin debe mantenerse refrigerada a 2-8C y utilizarse dentro de un plazo corto (habitualmente hasta 2-4 semanas segn el conservador del diluyente), evitando la exposicin prolongada a temperatura ambiente, la luz directa y los ciclos de congelacin-descongelacin, que degradan el pptido

Moreover, the FDA report references many instances where Novo Nordisk canceled, rejected, or failed to report multiple adverse drug experiences about patients taking semaglutide (the active ingredient in Rybelsus)

There are several oral antidiabetic (OAD) agents that may be used with MET, such as sulfonylureas (SU), meglitinides, thiazolidinediones (TZD), alpha-glucosidase inhibitors, dipeptidyl peptidase-4 (DPP-4) inhibitors, and sodium-glucose cotransporter-2 (SGLT2) inhibitors

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