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at China Pharmaceutical University and Nanjing First Hospital: oral Dihexa restored spatial learning and memory in the APP/PS1 transgenic mouse model of Alzheimers disease via the PI3K/AKT signaling pathway, reduced neuroinflammation, and preserved hippocampal synaptophysin expression (Sun et al., Brain Sciences 2021)
swelling of the lips and face, difficulty in breathing, skin rash and redness (these may be symptoms of a serious allergic reaction) irregular heartbeat (caused by low levels of potassium in the blood) duringearly stages of treatment
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