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doi: 10.1002/cncr.23527 145 OzHSChenTSMcclainCJDe VilliersWJ

Complications of nephrotic syndrome

Positive data readouts from outcome trials, a head start in negotiating access for these drugs with PBMs, and long lead times to ramp up manufacturing all contribute to a very significant competitive moat for both LLY and NVO as the GLP-1 market rapidly grows over the next decade

Whereas the AP lies outside the bloodbrain barrier and has a high density of Gipr -expressing cells, most of which are GABAergic, many Gipr -expressing neurones in the hypothalamus have their cell bodies behind the bloodbrain barrier and include both glutamatergic and GABAergic neurons 16