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Certain individuals should avoid tirzepatide
The most relevant data comes from a large phase 3 clinical trial (OASIS 4), published in the New England Journal of Medicine (2025)
The expression levels of chemerin and CMKLR1 are increased in degenerative NP tissues, especially those of obese individuals (31)
Conclusion Semaglutide treatment offers a promising solution for individuals struggling with type 2 diabetes and obesity
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