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Further tests on obese rats supported the idea that tesofensine could reduce body weight, so NeuroSearch decided to focus on developing it as an oral anti-obesity drug

Study monitoring Independent oversight committees included the Data Monitoring Committee (DMC), the Trial Steering Committee (TSC) and the Trial Management Committee, and were held on a regular basis throughout the trial

Presented for research literature review only Hawary OA et al

VadK does not transcriptionally regulate the MCC during propionate metabolism Bacterial histidine kinases are typically part of two-component regulators that modulate gene expression