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They are classified as bulk drug substances and are available only through a licensed prescribing provider and compounding pharmacy
" Patients negative for intrinsic factor antibody, with no other cause of deficiency, may still have pernicious anaemia and should be treated as anti-intrinsic factor antibody negative pernicious anaemia
Additionally, electrophysiological experiments have shown the direct effects of B vitamins on pain transmission pathways in the spinal cord and thalamus, which explains the observed reduction or loss of pain sensation in clinical patients
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