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Used in research and practice to assess tolerance before titrating up

For example, specific GLP1R or GIPR variants may correlate with appetite regulation patterns or metabolic response, helping contextualize whether a single GLP-1/GIP agonist or a different approach might fit your biology

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GLP 1RAs treatment, source: reference [1] Semaglutide Reduces Cardiovascular Disease Risk As obesity is an important risk factor for cardiovascular disease, weight loss should theoretically reduce the risk of cardiovascular disease in participants, however, this speculation has not been validated by clinical trials