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Recent technological advances allow quantification of over 600 metabolites from minimal sample volumes (1020 L), using high-throughput commercial platforms like Biocrates MxP Quant 500 (www.biocrates.com)
Al-Chalabi BM, Thanoon IA, Ahmed FA
The C-terminal amidation is critical for full biological activity, as the free-acid form shows significantly reduced receptor binding
Jan 28 2021;125(2):121-128
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