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As mentioned, a secondary analysis of an RCT assessing the cardiometabolic effects of exenatide in 40 people with schizophrenia 140 also looked at measures of cognition and psychosocial functioning (that is, Brief Assessment of Cognition in Schizophrenia, ReyOsterreith Complex Figure Test, Short-Form Health Survey, Personal and Social Performance Scale, Positive and Negative Syndrome Scale), but found no effect for this GLP-1RA compared with placebo over 3 months 133
Histamine is a chemical your body produces naturally
But every single person and every body is different
Therefore, the results indicate that the elevation of ROS damages neurons in the brain, leading to a loss of functionality, as evidenced by the increased lipid peroxidation and MDA levels
