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FIGURE 6 2.5 Skin fibrosis Hypertrophic scar is a prevalent yet inadequately resolved fibrotic dermatological condition, presenting as elevated, erythematous, indurated, and non-elastic plaques ( The pathogenesis of systemic sclerosis (SSc) is associated with endothelial damage, fibroproliferative vasculopathy, and fibroblast dysfunction (Taflinski et al., 2014
Try not to excessively cough, sneeze, or strain as this puts pressure on the puncture site which may cause it to bleed
At baseline, mean age was 47 years (range 18 to 80), 74% were female, 86% were White, 4% were Asian and 9% were Black or African American