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The chronic inflammation caused by autoimmune diseases can increase oxidative stress
doi: 10.1016/j.redox.2023.102855 73 HuangFWangQGuoFZhaoYJiLAnTet al
doi: 10.1093/carcin/bgae041 84
Starting at a lower dose allows tissues to respond without overstimulation, then the higher dose in Phase 2 extends and deepens that response
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