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While the total drug exposure remained comparable across all three sites, the thigh produced fewer acute gastrointestinal side effects in the study participants

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The effects of giving about a third of a teaspoon a day of powdered cinchona bark on satiety, weight loss, and body composition in a population of overweight adults. Significantly more weight loss, significantly more waist lost, and even slimmer hips in the bark group compared to placebo

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