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The weight-adjusted approach matters more for peptides with narrow therapeutic windows or those where body composition significantly affects distribution
doi:10.1016/j.numecd.2020.11.031 Monteleone G, Buchwald P, Inverardi L, Pileggi A, Ricordi C, Tomei A, Inventors
Obesity and Weight Studies: Published Phase 2 data (NEJM, 2023) showed up to 24.2% mean body weight reduction at 48 weeks
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