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The lack of HrpA/HrpB TPS in the gonococcus would explain why the gonococcus remains predominantly confined within a vacuole during cellular infection, unlike the meningococcus, which is able to escape, and why the meningococcus, after reaching the cytosol, induces pyroptotic pathways during cellular infection, a phenomenon not described for the gonococcus
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As we age, glutathione levels tend to decline in various tissues, putting cells at an increased risk of stress-related damage
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