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In a nine-month, randomized, double-blind, placebo-controlled study in 237 subjects with impaired glucose tolerance (pre-diabetes), no progression to overt diabetes was reported with a daily ingestion of a mixture of curcuminoids (0.5 g), while 16.4% of placebo-treated participants developed diabetes (71)

Hypoglycemia : Low blood sugar levels, or hypoglycemia, can occur, mainly when Semaglutide is used in combination with other medications like insulin or sulfonylureas

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Patients should inform their healthcare provider about: All current medications, including over-the-counter drugs and supplements Any history of pancreatic or kidney problems Previous diabetic retinopathy diagnosis Pregnancy plans or current pregnancy status When experiencing mild side effects that persist or become bothersome, patients should consult their healthcare provider rather than make medication adjustments independently [17]