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Studies demonstrate the peptide prevents NSAID-induced gastric ulcers and accelerates healing of existing ulcerations (Sikiric et al., Journal of Physiology and Pharmacology, 2017)
An animal study also shows that knockout specifically of SIRT1 in myeloid cells alleviates synovial inflammation and bone destruction of RA by decreasing Th1 and Th17 differentiation (304)
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