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In one trial, those switched to placebo injections not only began to reaccumulate body fat, but their waist circumference also began to revert back to its original size
Weight regain after discontinuing incretin-based therapies is well documented
As the parameters measured did not differ significantly between the two LC doses used, the study concluded that a low dose of LC was sufficient to render positive effects on pregnancy and offspring outcomes in pregnant mice [42]
The PICO model was applied in this study
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