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A recent meta-analysis evaluating the effects of GLP-1 RAs on depression found that these agents did not increase the risk of depression and may reduce depression scores [46]
The medication is administered as a once-weekly subcutaneous injection and functions through several mechanisms
While this mechanism reduces the risk of hypoglycaemia compared to some other diabetes medications, patients taking GLP-1s alongside insulin or sulfonylureas should be aware of an increased risk of low blood sugar and may need dose adjustments of these other medications
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