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Description

Sndergrd SD, Cintin I, Kuhlman AB, Morville TH, Bergmann ML, Kjr LK, Poulsen HE, Giustarini D, Rossi R, Dela F, Helge JW, Larsen S

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When ICDs are used in combination with immune checkpoint inhibitors (ICIs), the neoantigens they release, together with DAMPs, provide a dual antigen-adjuvant signal, while anti-PD-1/CTLA-4 antibodies form a triple antigen-adjuvant-unblocking of inhibition effect by relieving the inhibitory state of T cells (85)

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Respiratory suppression (although this is typically associated with much higher doses of phenobarbital than 20 mg/kg)

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Clinical Chemistry and Laboratory Medicine

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