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Suggested titration for sensitive individuals: Increase dose only if the current dose is well-tolerated
Collectively, these findings demonstrated that sulforaphane exert neuroprotective effect involving Nrf2-dependent reductions in oxidative stress, mTOR-dependent inhibition of neuronal apoptosis and the restoration of normal autophagy
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Spermatozoa are susceptible to oxidative stress due to a lack of their own cellular cytoplasmic antioxidants, high DNA susceptibility to oxidative damage, the presence of abundant polyunsaturated fatty acids (PUFAs) in their membrane, and high ROS production during their movements, generated by mitochondrial activity (18, 85, 89, 118)
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