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First, we leveraged a large, geographically diverse real-world database spanning multiple US health systems, enabling the evaluation of treatment effectiveness in a clinically relevant population of adults treated specifically for obesity managementrather than glycaemic control

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The structure of this review is based on a preliminary and theoretical model that incorporates and organises nutritional interventions into specific clinical and biochemical indications

If tolerating well with no GI issues and no hypoglycemia signals, increase to 500mg twice daily with two meals