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Arends, S
In a 48-week phase 2 trial in people with T2D and obesity, 10 mg/kg bimagrumab was associated with a marked reduction of fat mass (20.5% vs
Newer compounds like retatrutide act on three receptors simultaneously (GLP-1, GIP, and glucagon), combining appetite suppression with increased energy expenditure
5-amino-1mq appears to preserve muscle during fat loss, with studies showing treated subjects losing 10 to 15% less muscle than controls
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