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By utilizing a reversible, fluorogen-activated bimolecular complementation toolkit (FABCON) based on splitFAST, researchers can quantitatively track the dynamic association and dissociation of mito-LD foci during rapid shifts in lipid biogenesis and nutrient deprivation, thereby bypassing the irreversible tethering trap of traditional GFP sensors (212)

Moreover, oral semaglutide consistently reduced daily FI and progressively curbed BW gain in DIO mice

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