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Older people have weaker immune responses and are known to respond less well than younger adults to many vaccines, including the seasonal influenza vaccine

Interestingly, research has shown that even in animals lacking beta-3 adrenergic receptors, acute AOD-9604 administration still increased energy expenditure and fat oxidation, suggesting additional metabolic pathways may be involved beyond the primary beta-3 receptor mechanism

These include medications for acid reflux, synthetic estrogens, progesterone, (such as the birth control pill ), and antibiotics

However, whether the inhibition of enzymes involved in GSH biosynthesis induces ferroptosis has not been fully determined