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This difference is likely to be related to the more tightly packed ECD interface of RAMP2 and CTR, driven by the interactions with P37 Cagri , and the preferential CTR engagement by Cagri via a bypass conformation, as discussed below in the context of CTR complexes
Glucose homeostasis abnormalities can cause chronic hyperglycemia, triggering oxidative stress
Role of Finerenone in the treatment of diabetic kidney Disease: patient selection and clinical perspectives
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