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Clinical efficacy : Large randomised controlled trials demonstrate that GLP-1 receptor agonists can reduce HbA1c by approximately 1.01.5% and produce weight loss of 515% of body weight, with the higher end of weight loss typically seen with higher-dose semaglutide (2.4mg/Wegovy) specifically for obesity treatment

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An FDA-approved generic version of semaglutide wont be available until at least 2032 because the drug is still protected by a patent