Specific deletion of REST in NSCs, obtained by injecting a GFAP-Cre-p2A mCherry expressing retrovirus into the dentate gyrus of 6 to 8-week-old REST flox/flox (fL/fL) mice led to an increase of proliferating cells (Ki67-positive), as well as of neuroblasts and immature neurons (DCX-positive) and mature neurons (NeuN-positive)
The most common side effects, especially with excessive consumption that exceeds recommended amounts, include gastrointestinal discomfort, a fishy body odour and an increase in blood pressure
Yuan S, Wei C, Liu G, Zhang L, Li J, Li L, et al
The ATP7B gene is responsible for controlling the transport of copper from intracellular proteins into secretory pathways for excretion into bile and synthesis of ceruloplasmin (a protein that binds copper in the bloodstream)[7]