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REAs, though sensitive and efficient in reagent use, are limited by the need for radioactive isotopes and can only detect specific types of carnitines

Mild gastrointestinal symptoms (transient nausea, vomiting, abdominal cramps and diarrhea) have been reported

High density lipoprotein (HDL) reverses palmitic acid induced energy metabolism imbalance by switching CD36 and GLUT4 signaling pathways in cardiomyocyte

Calculating 13 C-labelling enrichment in the detected metabolites The distribution of 13 C-labelling from arginine or proline in the identified metabolite pool was determined by calculating the ratio of 13 C to 12 C in the major mass fragments