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For weight management, Wegovy (semaglutide) is the licensed product, and NICE guidance (TA875) recommends its use only in specialist weight management services for a maximum of 2 years

This rapid degradation is the primary reason that GLP-1 receptor agonist drugs require structural modifications such as DPP-4 resistance mutations, albumin binding, or Fc fusion to achieve a pharmacologically useful duration of action

Rapid weight loss can leave people with sagging skin, hollow cheeks, and weakened muscle tone, Marcelino explains

Large, unverified doses of antioxidant blends sometimes promote metabolic claims beyond the evidence