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The most important reactions requiring ascorbate as a cofactor are the hydroxylations of lysine and proline residues in collagen
Melanin can also inactivate reactive oxygen species and free radicals, can sequestrate redox-active metals and organic toxic compounds, can neutralize bacteria-derived enzymes and toxins, and can downregulate inflammatory processes [4, 6, 7]
Similar effects were observed with neural stem cell or bone marrow stromal cell injections
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