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InThought: Takeda is positioning the drug as a first-in-class disease- modifying therapy for narcolepsy type 1 (NT1), directly addressing orexin deficiency rather than merely managing symptoms
In a Phase 2 trial that was published in the The New England Journal of Medicine participants achieved up to 24.2% average body weight loss at 48 week s while some higher dose groups gained 17.5% weight loss within just 24 weeks
At superficial levels, it smooths texture and clears pigmentation
Phosphorylation of PFKL regulates metabolic reprogramming in macrophages following pattern recognition receptor activation
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