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Akhter, A
These are very, very natural products
2.4 Microbiome-Endocrine integration (hours to days) Dysbiosis reshapes the bile-acid pool via microbial bile-salt hydrolase (BSH) activity, modulating farnesoid X receptor/Takeda G-protein-coupled receptor 5 (FXR/TGR5) signaling (preclinical), and microbiota-derived bile acids/short-chain fatty acids (SCFAs) can influence L-cell GLP-1 secretion, helping explain variability in subsequent postprandial responses (foundational preclinical listed in Supplementary Table S1
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