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The immune system clearly plays a central role, in particular Th1 and Th17 cells, along with cytotoxic T cells, regulatory T cells, and dendritic cells
Only about 1% of the oral dose is absorbed, which is why 50 mg oral tablets are needed to match blood levels achieved by 2.4 mg weekly injections
Epidermal growth factor increases collagen production in granulation tissue by stimulation of fibroblast proliferation and not by activation of procollagen genes
Additional information Communicating editor: Michael Gibson Competing interests: None declared Rights and permissions About this article Cite this article Silva, M.F.B., Aires, C.C.P., Luis, P.B.M
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