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Patients should not advance to higher doses if they are experiencing significant side effects at their current dose level

Kushner, an obesity medicine specialist and Northwestern University professor emeritus, recommends eating slowly, in smaller portions, and avoiding fatty or greasy foods that may cause bellyaches

When appetite is low, protein, fiber, fluids, and micronutrients all have to fit into less food than usual

After 3 days, the culture medium was replaced by control medium (-MEM with 10% FCS 1% P/S) or osteogenic medium (-MEM 10% FCS 1% P/S, 0.052 mg/mL dexamethasone, 12.8 g/mL ascorbic acid and 2.15 mg/mL -glycerophosphate (Sigma-Aldrich) for 1214 days