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Those medications work by binding directly to GLP-1 receptors at pharmacological doses
This contributes to reduced collagen production, chronic inflammation and the buildup of senescent cells (sometimes called zombie cells) that weaken the skins structure over time[1]
Pharmacological treatment of painful HIV-associated sensory neuropathy: a systematic review and meta-analysis of randomised controlled trials
The medication also slows gastric emptying, meaning food stays in the stomach longer, reinforcing fullness signals
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