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Measurements included hydrodynamic diameter (2RH), polydispersity index (PDI) and zeta potential (ZP) (Table 1), which were obtained using dynamic light scattering (DLS) with a NanoBrook Omni analyzer (Brookhaven Instruments Corporation, Holtsville, NY, USA)

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[18] [19] More precise quantification can be achieved through imaging modalities such as magnetic resonance imaging (MRI) or computed tomography (CT), though these are typically reserved for research settings or specific clinical indications due to cost and, in the case of CT, radiation exposure

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