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If improvements plateau or regress during the off period, this data helps your provider decide whether another cycle is warranted
Individual Side Effects: What to Expect and How Community Sources Manage Each Nausea Frequency: 27% of trial participants Onset: 1-4 hours post-injection Duration: 4-8 hours typically Severity: Dose-dependent, most severe weeks 1-6 Nausea is the hallmark side effect of retatrutide, though it occurs less frequently than with high-dose tirzepatide (up to 45% at 15 mg)
Long-term treatment may bring life changes that affect mood, including body image shifts, changed eating patterns, social attention, or pressure to maintain weight loss
It can cause constipation if used regularly
