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These observations were further confirmed by Hoechst 33342 staining, which revealed extensive detachment of cells from the cell culture substratum and increases in apoptotic bodies of HepG2 cells incubated with H 2 O 2 and TNF for 16 h (Fig
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Additionally, IGF-1 supports tendon healing by stimulating collagen I production and tenocyte proliferation, improving structural integrity and recovery outcomes (5)
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