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Starting from a therapeutic dose of 15 mg weekly, the schedule uses the same four-week intervals between each dose reduction
4 Adverse events in PIONEER 3 1,4 Comparator AE rates are not an adequate basis for comparison of safety between products 1 Because clinical trials are conducted under widely varying conditions, AE rates observed in the clinical trials of a drug cannot be directly compared with rates in the clinical trials of another drug and may not reflect the rates observed in practice 1 AE=adverse event
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Because semaglutide GLP-1 is usually increased slowly, the full effects may become stronger as the dosage reaches higher levels
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