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The sexual dimorphism in NAFLD has been increasingly attributed to beneficial actions of estrogens on lipid metabolism (76)

Nausea that lasts longer or becomes severe might point to gastroparesis rather than normal medication effects

In spontaneously hypertensive rats (SHRs), a model of stroke-prone hypertension, a marked reduction in endothelial TJ expression precedes the onset of hypertension and is associated with an increased risk of BBB disruption and cerebrovascular events, such as stroke [164]

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